Building Blocks

BioBlocks offers a focused collection of over 3900 scaffolds, building blocks and fragments which are pre-qualified as drug components. The majority of these compounds are uniquely offered by BioBlocks and have found applications ranging from intermediates for drug discovery to surrogate amino acids in peptide chemistry.


Search our entire building blocks collection by structure

All of BioBlocks’ building blocks have been successfully synthesized. In-stock items are typically available in 1 g – 100 g quantities. Larger amounts, up to multiple kilograms, are also available. We also offer the synthesis of small focused libraries based on BioBlocks’ scaffolds. Please contact BioBlocks directly for quotes for kilo-scale orders and focused libraries.

Attractive discounts are available for companies purchasing larger quantities of building blocks, multiple items or assembling compound kits For further information, write us at sales@bioblocks.com, or call Customer Service at 858-558-5900.

Quinolines

Entire quinoline collection

Quinoline carboxylic acids
and derivatives

4-Chloro-Quinolines

4-Hydroxy-Quinolines

Piperazinyl-Quinolines

Bromo-Quinolines


2-Chloro-Quinolines

4-Amino-Quinolines

3-Iodo-Quinolines
3-Iodo-Quinolines
Newsletters
2- and 4-Piperazin-1-yl-quinolines | 3-Amino-quinolines and 3-Carboxyl-quinolines | Quinoline Amino Acids and Esters | Carboxylate and Bromo-nitrile Quinolines Available | 3-Bromo-4-hydroxy-quinolines | 4-Chloro- and 4-Amino-quinolines | Fluoroquinolines | Chloroalkyl-quinolines | Trifluoromethyl quinolines | 2-Hydrazino quinolines | 4-Bromo quinolines

Learn more about quinolines and their applications here.

Beta Amino Acids and Derivatives

Cyclic Beta Amino Acids
5- and 6- membered rings
7- and 8- membered rings
Bicyclic systems

Acyclic Beta Amino Acids

Chiral Beta Amino
Acids and Derivatives

Beta Amino Esters

Boc Protected
Cbz Protected
Fmoc Protected

Beta Amino Amides

3- Amino Alcohols

2- Amino Alcohols
Newsletters
Self-organizing systems - Foldamers | Chiral amino acids | Versatile Beta amino acids

Learn more about beta-amino-acids and their applications here.

Benzyl Piperidines

4-Benzyl-Piperidines


3-Benzyl-Piperidines

2-Benzyl-Piperidines

Learn more about benzyl piperidines and their applications here.

Heterocycles
Selected examples:
View the entire BioBlocks Heterocycle product set
Newsletters
Imidazoles, oxazoles and thiazoles in Medicinal Chemistry

Kinase Targeted Amines

4-aminoanilines

4-benzylaminoanilines

4-phenethylaminoanilines
Newsletters
Kinase targeted amines (kinamines)

Bode Chiral Auxiliaries

AX001

AX002
References
Chem. Sci., 20101, pp 637-641

Cyclopropyl Phenyl Acids and Derivatives

Cyclopropyl Phenyl Acids

Cyclopropyl Phenyl Methylamines

Cyclopropyl Phenyl Nitriles
Newsletters
Cyclopropyl Phenyl Series in Medicinal Chemistry

Bode Organocatalysts

BC001-1

BC002-1

BC003-1

BC003-13
References
J. Am. Chem. Soc., 2009131, pp 8714–8718

Phenyl Aziridines

cis-Phenyl Aziridines

trans-Phenyl Aziridines

Additional Product Classes

Anthranilamides

Quinazolines

Thiadiazoles

Triazoles

Hydroxymethyl Pyrazoles
Newsletters
2-Carboxy-quinazolines